Document Type

Patent

Publication Date

1-11-2011

Patent Number

patent number 7867985

Abstract

Fluid compositions and methods for lubrication of mammalian joints are disclosed, including both natural and artificial fluids. Synovial fluid acts to lubricate the bearing surfaces of bones and bone-like structures which are held in frictional contact within biological joints. Such fluids may be used to treat arthritic, injured, and diseased joints. Synovial fluid containing a dextran-based hydrogel with lipids provides enhanced rheological and tribological properties of such a fluid. Phospholipids are particularly useful in dextran-based compositions for synovial fluid. One phospholipid that can be used advantageously in synovial fluid is dipalmitoyl phosphatidylcholine (DPPC).

Application Number

10/853611

Assignees

Clemson University Research Foundation (Clemson, SC, US)

Filing Date

2004-05-25

Primary/U.S. Class

514/59

Other/U.S. Class

536/112

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