Document Type
Patent
Publication Date
10-14-2014
Patent Number
Patent Number 8858979
Abstract
A composite material including ultra-high molecular weight polyethylene in conjunction with a biologically active agent is described. The biologically active agent can be, for example, an anti-osteolytic agent such as a bisphosphonate. The composite material can be utilized in forming implants such as total joint replacement implants. The biologically active agent can be released from the composite material either from the bulk or from wear particles released from the surface of the implant component during use. Upon release, the biologically active agent can carry out the intended function of the agent.
Application Number
13/360,020
Assignees
Clemson University, Clemson, SC (US)
Filing Date
2012-01-27
Primary/U.S. Class
424/423
Other/U.S. Class
427/2.27; 623/16.11