Document Type

Patent

Publication Date

12-13-1994

Patent Number

patent number 5372818

Abstract

A novel method for using domperidone, a dopamine receptor antagonist, for treating fescue toxicosis in animals is provided. Fescue toxicosis is caused by animals grazing on endophyte-infected fescue grass. Treatment of the animal with various dosages of domperidone results in effective management of the toxin. The domperidone treatments do not cause any substantial adverse behavioral or neurological side effects in the animal. Domperidone is a more effective treatment for fescue toxicosis than previously-known agents such a metoclopramide and sulpiride.

Application Number

08/012296

Assignees

Clemson University (Clemson, SC)

Filing Date

1993-02-01

Primary/U.S. Class

424/442

Other/U.S. Class

514/276, 514/450

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