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Authors

Mary Tobin

Abstract

Lyme Infection-Associated Chronic Illness (Lyme IACI) is a term adopted by the U.S. National Academies of Sciences, Engineering, and Medicine (NASEM) to describe persistent, often debilitating symptoms that follow Lyme disease infection. Affecting an estimated 10–20% of individuals treated for Lyme disease, Lyme IACI includes fatigue, musculoskeletal pain, cognitive dysfunction, and sleep disturbances that can last months or even years despite standard antibiotic therapy (NASEM, 2025). Unlike acute Lyme disease, Lyme IACI is not well understood and lacks validated diagnostic tools or biomarkers, making it a challenge to diagnose or treat for clinicians and caregivers—especially those working with children in camp settings.

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