Identification and Functional Evaluation of Anti-Cancer Ilmmunomodulators from Physalis peruviana (Poha)

Authors

Haley Huggins, Clemson University
Stephanie Brierley, Clemson University
Alyssa Shearer, Clemson University
Alicia Burns, Clemson University
Iris Yang, Clemson University
Ashlee Tietje, Clemson University
Yanzhang Wei, Clemson University

Document Type

Poster

Publication Date

Spring 2015

Abstract

Our Creative Inquiry team is researching the anti-tumor potential of compounds isolated from Physalis peruviana (poha) fruit. CellTiter 96 Aqueous Non-radiative Cell Proliferation Assays (Promega, 2012) were performed to screen the inhibitory activity of the compounds on human lung carcinoma A549 cells and breast cancer MDA-MB- 231 cells with the corresponding non-tumorigenic epithelial cell line NL20 and MCF-10A as controls. The cells were treated with compounds at concentrations of 0μg/ml, 2μg/ml, 5μg/ml, and 20μg/ml and incubated for 24, 48, and 72 hours.

Comments

Poster presentation at Clemson University 10th Annual Focus on Creative Inquiry Forum, Clemson, SC.

Recommended Citation

Huggins, Haley; Brierley, Stephanie; Shearer, Alyssa; Burns, Alicia; Yang, Iris; Tietje, Ashlee; and Wei, Yanzhang, "Identification and Functional Evaluation of Anti-Cancer Ilmmunomodulators from Physalis peruviana (Poha)" (2015). Focus on Creative Inquiry. 130.
https://open.clemson.edu/foci/130