Date of Award
12-2023
Document Type
Dissertation
Degree Name
Doctor of Philosophy (PhD)
Department
Chemistry
Committee Chair/Advisor
Prof. Leah Casabianca
Committee Member
Prof. Jason McNeill
Committee Member
Prof. Julia Brumaghim
Committee Member
Dr. Modi Wetzler
Abstract
The objective of the thesis is to study the effect of environmental pollutants on polystyrene nanoparticles and biomolecules. This is done in two different techniques, particularly NMR and density functional theory. In this thesis, we use a combination of 1H NMR, Saturation-Transfer Difference (STD) NMR and relaxation experiments to study the interactions, kinetics and dynamics of antibiotics with polystyrene nanoparticles. (PS NPs) Density functional theory (DFT) is used to study the binding of commonly used non-oxidative hair dyes to biomolecules (DNA and amino acids) and PS particles.
Recommended Citation
Arachchi, Saduni, "Understanding the Interaction of Environmental Contaminants With Polystyrene Nanoparticles and DNA Using Nuclear Magnetic Resonance Spectroscopy and Density Functional Theory" (2023). All Dissertations. 3543.
https://open.clemson.edu/all_dissertations/3543