Date of Award
12-2025
Document Type
Dissertation
Degree Name
Doctor of Philosophy (PhD)
Department
Nursing
Committee Chair/Advisor
Luigi Boccuto
Committee Member
Delphine Dean
Committee Member
Diana Ivankovic
Committee Member
Lucia Gonzales
Abstract
Early in the pandemic, doctors noticed many people developed long-lasting problems after COVID-19, affecting the brain, heart, stomach, liver, and kidneys. These ongoing health effects have since been the subject of many studies.
Currently, there are no clear diagnostic guidelines that clinicians and healthcare personnel can use when encountering patients with LC-19-like symptoms. This has resulted in much confusion and delayed diagnosis, with severe impacts on the parties concerned, warranting the need for the public health authorities or health regulatory bodies to establish clear rules and avoid underreporting or misdiagnosing cases.
This disease has components that involve more than just physical symptoms. There are social and psychological aspects that may exacerbate the patient's suffering that are more than just physical. Thus, there is a need to treat the LC-19 patients or those suspected of having the condition on a holistic level to address all aspects of this disease.
Finally, in the study, we attempted to find a metabolic signature unique to the LC-19 group. These metabolic changes could be helpful in both easing the diagnostic journey and finding sites for therapeutic intervention.
Recommended Citation
Srikanth, Sujata, "Metabolic Signatures of Long COVID-19" (2025). All Dissertations. 4167.
https://open.clemson.edu/all_dissertations/4167
Author ORCID Identifier
0000-0001-9962-2800
Included in
COVID-19 Commons, Diseases Commons, Medical Physiology Commons, Molecular Genetics Commons, Physiological Processes Commons, Physiology Commons, Public Health and Community Nursing Commons