Date of Award
12-2006
Document Type
Thesis
Degree Name
Master of Science (MS)
Legacy Department
Bioengineering
Committee Chair/Advisor
Burg, Karen J.L.
Abstract
The purpose of this study was to develop and assess a potential key feature in a minimally-invasive breast reconstruction device and to collect information for an in vitro tissue test system. Tannic acid is a hydrolysable plant tannin, and it has been determined that tannic acid functions as a collagen crosslinking agent through both hydrogen bonding mechanisms and hydrophobic effects. Additionally, current research suggests that tannic acid may have anti-tumor properties. Therefore, it has been proposed that tannic acid can be used as an agent to induce apoptotic processes in any transplanted adult stem cells that are inclined to spontaneously transform. Furthermore, collagen scaffolds can be used as a vehicle to deliver tannic acid to the tissue margins surrounding a tumor following a lumpectomy procedure as a form of adjuvant therapy.
Recommended Citation
Parzel, Cheryl, "Tannic Acid Crosslinked Collagens and Potential for Breast Tissue Engineering" (2006). All Theses. 33.
https://open.clemson.edu/all_theses/33