Document Type
Article
Publication Date
4-4-2020
Publication Title
Journal of Cardiovascular Translational Research
Publisher
Springer Nature
DOI
10.1007/s12265-020-09993-4
Abstract
We developed models of pulmonary artery (PA) size in Fontan patients as a function of age and body surface area (BSA) using linear regression and breakpoint analyses based on data from 43 Fontan patients divided into two groups: the extracardiac conduit (ECC) group (n = 24) and the non-ECC group (n = 19). Model predictions were compared against those of a non-Fontan control group (n = 18) and published literature. We observed strong positive correlations of the mean PA diameter with BSA (r = 0.9, p < 0.05) and age (r = 0.88, p < 0.05) in the ECC group. The absolute percentage differences between our BSA and age model predictions against published literature were less than 16% and 20%, respectively. Predicted PA size for Fontan patients was consistently smaller than the control group. These models may serve as useful references for clinicians and be utilized to construct 3D anatomic models that correspond to patient body size or age.
Recommended Citation
Gupta, A., Gillett, C., Gerard, P. et al. Predictive Models for Pulmonary Artery Size in Fontan Patients. J. of Cardiovasc. Trans. Res. (2020). https://doi.org/10.1007/s12265-020-09993-4
Supplemental File
Comments
This manuscript has been published in the Journal of Cardiovascular Translational Research. Please find the published version here (note that a subscription is necessary to access this version):
https://link.springer.com/article/10.1007%2Fs12265-020-09993-4#citeas