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Theses from 2024

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Broadening the Application Range of Cell-Free Protein Expression Systems, Matthew Becker

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The Effect of Central Screw and Post Vault Containment on Reverse Total Shoulder Arthroplasty (RSTA) Baseplate Stability, Mickaela J. Gunnison

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Development of a Cost-Affordable Thin-Layer Chromatography Testing Kit for Falsified and Substandard Pharmaceuticals in Tanzania, Eleanor Hatcher

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A Benchtop Analysis of Pressure Offloading Associated With Custom Socket Inlays in Transtibial Prostheses, Sarah G. Hill

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Advancements of a Breast Tissue Marker and Localization System, Azrin Jamison

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Expandable Tissue-Engineered Living Surgical Pulmonary Heart Valve for Pediatric Patients, Jacob M. Lautenschlager

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Evaluation and Development of Tourniquet Test Methods, Catherine Pitts

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Hand Movement Analysis for Surgical Suturing Skill Assessment, Amir Mehdi Shayan

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The Effect of Football Facemask Design Variability on Dynamic Impact Performance and Quasi-Static Stiffness, Adam W. Smith

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Hyperspectral Image Classification of Bacteria Using a Deep Convolutional Neural Network, Bruce S. Vogelsberg Jr

Theses from 2023

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1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine (MPTP)-Treated Adult Zebrafish as a Model for Parkinson’s Disease, Emmeline Bagwell

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The Effects of Compression Wrapping Techniques and Primary Wound Dressings on Leg Skin Interface Pressure, James Cox

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Tandem Peptides Targeting HER2 for Delivery of CD44 siRNA into HER2+ Breast Cancer Cells in Vitro, James Kalogeros

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Multiplex Gene Editing in Hepatocytes as a Therapeutic Approach for Familial Hypercholesterolemia, Sarah Minich

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Effects of IVD-Like Pressure and pH on Human Adipose Derived Mesenchymal Stem Cells, Alexandria Pendino

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Medical Simulation-Based Sensor Methods for Ultrasound-Guided Dialysis Cannulation Skill Assessment, Devansh Shukla

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An In Vivo Biocompatibility Analysis of A Novel Tissue Regeneration Matrix Using A Pig Model, Shamar Thomas

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Photodynamic Therapy to Treat Triple Negative Breast Cancer in Vitro, Hunter S. Warren

Theses from 2022

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Variations in Surgeon-Applied Loads During Passive Range of Motion Following Total Knee Replacement With Relevance To Computational Modeling, CJ Bakle II

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Design of a Four Channel Pulsatile Perfusion Bioreactor for ex-Vivo Study of Vascular Grafts, Thomas M. Fair

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Fabrication of Hydrogel Microparticles for Acute Treatment of Penetrating Brain Injuries, Isabell Foulger

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Tissue-Engineered Living Pulmonary Valve for Young Adult Patients, Erica Hoskins

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A 3D Tissue Engineering Model to Study Mitral Valve Annulus Calcification under Diabetic Conditions, Erin James

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Nonlinear Optical Microscopy Assessment of Tissue Structure and Chondrocyte Viability of Articular Cartilage, Michael Le

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Portable U-Bent Optical Fiber Biosensor for Detecting Microcystin-LR, Quan Dio Anh Le

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Optimizing CRISPR/Cas9-mediated knockdown of ANGPTL3 in liver cell lines and mouse hepatocytes, Meredith Reeves

Theses from 2021

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Site-specific Nanoparticle Therapy for Treatment of Medial Arterial Calcification, Tyler James Gibson

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In Vivo Analysis of an Injectable Tannic Acid Crosslinked Collagen Type I Bead Scaffold for Tissue Regeneration Post-Lumpectomy, Kylie King

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Bovine Intervertebral Disc Organ Culture for Assessing Regenerative Therapeutics for Herniation Repair, Mario Josef Krussig

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Investigation on Effects of Lactate Adaptation Using Metabolic Indicators and Amino Acids to Explore Cell Metabolism, Lisa Uy

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Diagnosis of Myocardial Hypertrophic Disease States Through Machine Learning and Mechanistic Modeling, Michael William Ward

Theses from 2020

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The Fabrication and Analysis of an Angle-Ply, Multi-Laminate Annulus Fibrosus Plug for Intervertebral Disc Repair, Alex Garon

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Design and Development of an Unconstrained Spine Test Rig to Study the Kinematics of Spine Motion, Nisha Gulhane

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Effect of Aging Time on Stiffness in Acid Catalyzed Silica Sol-Gels, Satya Kalidindi

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Mechanical Analysis of Double Network Hydrogels to Determine Suitability as an Articular Cartilage Substitute, Casey Virginia Young

Theses from 2019

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Lectin Coated Electrodes For Biosensor Water Testing Applications, Aniqa Nuzhat Chowdhury

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An Ex Vivo Model of Elastin Degradation in Porcine Carotid Arteries for the Study of Abdominal Aortic Aneurysms, Hannah Gore

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Investigating Low Culture Temperature and Low Media pH of Two Chinese Hamster Ovary (CHO) Cell Lines with Next Generation RNA Sequencing (RNA-Seq) Technology, Timothy James Lindquist

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Differential Gene Expression in Tendinopathy: Insights into the Failure of Wound Healing, Michael Maggio

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A Multimodal Exploration of Altered Mechanical and Histological Properties in Tendons with Degenerative Tendinopathy, Olivia Newkirk

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Microfabricated Substrate to Achieve In Vivo-Like Cardiomyocyte Morphology and Electrical Propagation in Neonatal Cell Culture, Tiffany Yu

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Reprocessing Protocol Validation for Medical Devices Used in Low-Resource Settings, Sarah Zemitis

Theses from 2018

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System for the Application of Hydrostatic Pressure and Mechanical Strain to Cell Cultures, Justin Bacaoat

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A Computational Model of the Pulmonary Fibroblast Signaling Network as Related to Idiopathic Pulmonary Fibrosis, Jessica Lennox Batista

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Effect of Total Knee Replacement Conformity on Articular Constraint in Mechanical Testing, Madeline Bebler

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Comparing the Therapeutic Efficacy of Human Amniotic Membrane and Adipose-Derived Mesenchymal Stem Cells in Mitigation of Osteoarthritis, Mackenzie Catherine Bowman

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Stretching Vascular Smooth Muscle Cells on Micropatterned Surfaces, Suzanne Nicole Bradley

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Vascular Tissue Engineering in Metabolic Syndrome Conditions – in vitro Studies, Anna Lu Carter

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Regeneration of the Ventricular Endocardium Within Acellular Whole Rabbit Hearts Using a Layer-by-Layer Seeding Method, Clayton Lewis Compton

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Quantitative Histological Analysis of Fixation Points on Explanted Hernia Mesh, Brittney Cotton

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Self-Assembling Peptide Hydrogel for Local Anticancer Prodrug Delivery in the Treatment of Glioblastoma Multiforme, Arica Gregory

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Micromotion and Strength of the Glenoid Component in Reverse Total Shoulder Arthroplasty: The Effect of Malpositioning Versus Optimal Clinical Positioning in the Simulated B2 Glenoid, Shannon Hall

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Liposomal Combination Drug and siRNA Delivery to Combat Drug-Resistant Ovarian Cancer, Emily Margaret Miller

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Combinatorial Therapy of Doxorubicin and MDR1 SiRNA by Polymeric Micellar Nanoparticles in Treatment of Multidrug Resistance in Breast Cancer, David Lamar Oglesby

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Histological Evaluation of the Effects of Diabetes on Renal Vasculature, David Pollard

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The Detrimental Effects of Cigarette Smoke on Fracture Healing in a Bilateral Femur Fracture Rodent Model, Russell Abbott Reeves

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Mechanical Characterization of the Mesh-Tissue Composite Using Abdominal Wall Tissue Phantoms and Experimental Simulations, Mathew Murphy Stanford

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A Sensor Based Approach to Analyzing Motion in Medical Applications: AV Fistula Cannulation and Rett Syndrome, Jared J. Wells

Theses from 2017

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Fabrication and Characterization of Electrospun Anti-Proliferative Sutures for Vascular Applications, Erica Beal

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The Effect of Hydrostatic Pressure on Neuronal Cell Morphology In Vitro, Kallie Etten

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Evaluating Stem Cell Response to a Spider Silk Scaffold, Katherine Lee Hafner

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Novel device for improved diagnosis and monitoring of rotator cuff injury, Brittany Nicole Hall

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Improving Cell Seeding of Decellularized and Porated Porcine Arterial Scaffolds, Harrison Smallwood

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The Effect of Surface Roughness Modifications and Chitosan Surface Coatings on Biofilm Formation for Prevention of Orthopaedic Infections, Nathan Dewayne Smith

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Formulating a composite scaffold with tissue regeneration and anti-cancer activity, Kendyl Marie Williams

Theses from 2016

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Controlling Thermal Gelation Properties of Novel Tetronic® Hydrogel-Based Tissue Adhesive, Martin Fernando Alejos

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Characterization of Smooth Muscle Cells and Urothelial Cells Differentiated from Human Adipose Derived Stem Cells for Seeding a Bladder Tissue Biomimetic Patch, Caitlyn Ambrose

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Glenoid Baseplate Micromotion in Reverse Total Shoulder Arthroplasty, Jennifer Kristin Anderson

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Cell Source Optimization for Cardiac Tissue Engineering, Joshua Biggs

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Endothelialization of the Coronary Vasculature in Decellularized Heart Scaffolds, Jessica Lan Canavan

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Proof of Concept for a Urine-Based Method for Monitoring Blood Phenylalanine for Patients with PKU, Alexandra Cholewczynski

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Development of Low-Cost Impedimetric Biosensors for Clinical Diagnostics and Water Testing, Andrew Lehron Cobb

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Fabrication and Characterization of an Extracellular Matrix Hydrogel for Aortic Valve Applications, Brady Culbreth

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Fabrication and Characterization of Heparin-Immobilized Electrospun Nanofibers for Vascular Suture Applications, Michael J. DiBalsi

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Characterization of Particulate in Vacuum Casting for Long Term Space Flight, Devin Elizabeth Gibson

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In Vitro Studies of Heparin-Coated Magnetic Nanoparticles for Potential Use in the Treatment of Neointimal Hyperplasia, Andrew Hargett

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Development and Initial Validation of a Surgical Instrument for In Situ Mechanical Characterization of Surgical Mesh-tissue Composites, Jorge Ivan Hernandez Sanchez

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Design and Manufacture of a Biodegradable Ureteral Stent, James Hyde

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Tannic Acid Crosslinked Collagen Type I for Prevention of Local HER2-Positive Breast Cancer Recurrence, Lauren Gayle Jordan

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Cellular Interactions Underlying Vascular Calcification in Diabetes, Lisa Ann Larrew

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Development of a Tissue-Mimicking Brain Phantom for Neurosurgical Pre-Operative Planning and Training, Miriam Navarro Lozoya

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Electrophysiological Characterization of Cardiac Cells Differentiated from Embryonic, Induced Pluripotent and Adipose-Derived Stem Cells for Translational Tissue Engineering Applications, Robert Marti

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The Development of a Biomimetic Patch for Annulus Fibrosus Repair, Rachel Michelle McGuire

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Simulating Burial Settings: Laboratory-Scale Forensic Bioreactor, VeeAnder Sheldonia Mealing

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Immunomodulatory Effects of Human Adipose Derived Stem Cells on Human Macrophages in Diabetic Environment, Maria Margarita Portilla

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An Investigation Into The Effects Of Low-Dose Gamma Radiation On Porcine Digital Flexor Tendons, Megan Keira Robson

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The Cellular and Molecular Characterization of Essential Hypertension Using Innovative Pathology Models, Joshua T. Rodriguez

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Autologous Protein Solution Exhibits Potential to Mitigate Osteoarthritis (OA) Progression in a Human Explant Co-Culture Model, Kathleen Emily Steckbeck

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Design and Initial Verification of a Novel Total Knee Replacement that Incorporates Synthetic Ligaments to Influence Knee Stability, Michael David Stokes

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Fabrication and Characterization of a Novel Porous Polymer Microsphere - Hydrogel Composite for Cell Therapy, Prathik Thulluri

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Proof of Concept Studies for Point of Care Rotator Cuff Tissue Engineering, Alison Welch

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Endothelialization and In Vitro Characterization of a Small Diameter Tissue Engineered Vascular Graft for Patients with Diabetes, Eric Brandon Wright

Theses from 2015

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Characterization of a Multi-Laminate Angle-Ply AF Patch for Annulus Fibrosus Repair, Ryan Borem

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PHYSICAL CHARACTERIZATION OF SURGICAL MESH AFTER FUNCTION IN HERNIA REPAIR, Erin McClure Casey

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Influence of low shear and cyclic strain on hyperglycemic rat aortic smooth muscle cells: An In Vitro dynamic disease model, Varun Chawla

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DECELLULARIZED BOVINE NUCLEUS PULPOSUS AS A BIOMIMETIC SCAFFOLD FOR INTERVERTEBRAL DISC REGENERATION, Christopher Fernandez

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Endothelialization Using Protein Substrates and Hydrogels for Aortic Valve Applications, Elizabeth A. Fontaine

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Bioprinting as a Tool to Evaluate Interactions of Cancerous and Noncancerous Cells, Holly Jordan

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Micro and Molecular Phase Modulation for Long-Lasting Absorbable, Compliant Polymers for Orthopedic Applications, John Aaron Lilley

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Analyzing User Acceptance of Mobile Technology in Clinical Settings through Point-of-Care Mobile Applications, Leanne Elizabeth Loper